ORKAMBI® (lumacaftor/ivacaftor) Mechanism of Action Download

ORKAMBI® (lumacaftor/ivacaftor) | Official HCP Site - Official healthcare provider website for ORKAMBI® (lumacaftor/ivacaftor). Includes important safety information.

http://www.orkambihcp.com/important-safety-information ORKAMBI® (lumacaftor/ivacaftor) Important Safety Information - ORKAMBI® (lumacaftor/ivacaftor) Important Safety Information for Healthcare Professionals

http://www.orkambihcp.com/impact-of-disease/f508del-mutation Homozygous gene mutation - Healthcare provider information is provided on the prevalence and impact of a specific gene mutation

http://www.orkambihcp.com/mechanism-of-action ORKAMBI® (lumacaftor/ivacaftor) Mechanism of Action - Here healthcare providers can learn about the mechanism of action of ORKAMBI® (lumacaftor/ivacaftor) as well as click on an interactive illustration

http://www.orkambihcp.com/clinical-trials/trial-design ORKAMBI® (lumacaftor/ivacaftor) Trial design - Design of Trials 1 and 2 of ORKAMBI® (lumacaftor/ivacaftor) including primary and secondary endpoints is provided for healthcare providers

http://www.orkambihcp.com/clinical-trials/efficacy-summary ORKAMBI® (lumacaftor/ivacaftor) Efficacy data - Here healthcare providers can review a summary of clinical efficacy data for ORKAMBI® (lumacaftor/ivacaftor), including primary and secondary endpoints

http://www.orkambihcp.com/clinical-trials/lung-function ORKAMBI® (lumacaftor/ivacaftor) Clinical Data - Clinical efficacy data is provided for healthcare providers on ORKAMBI® (lumacaftor/ivacaftor)

http://www.orkambihcp.com/clinical-trials/BMI ORKAMBI® (lumacaftor/ivacaftor) Secondary Efficacy Endpoints - Secondary efficacy endpoint data is provided for healthcare providers on ORKAMBI® (lumacaftor/ivacaftor)

http://www.orkambihcp.com/clinical-trials/cfq-r ORKAMBI® (lumacaftor/ivacaftor) Secondary Endpoints - Secondary endpoint data is provided for healthcare providers on treatment with ORKAMBI® (lumacaftor/ivacaftor)

http://www.orkambihcp.com/safety-profile ORKAMBI® (lumacaftor/ivacaftor) Safety Profile - Safety profile including side effect information is provided to healthcare providers for ORKAMBI® (lumacaftor/ivacaftor)

http://www.orkambihcp.com/dosing/dosage-and-administration ORKAMBI® (lumacaftor/ivacaftor) Dosing information - Healthcare providers can review the recommended dosage and dose adjustments for ORKAMBI® (lumacaftor/ivacaftor)

http://www.orkambihcp.com/dosage-and-administration/orkambi-drug-interactions ORKAMBI® (lumacaftor/ivacaftor) Drug interactions - Healthcare providers can review potential drug interactions with ORKAMBI® (lumacaftor/ivacaftor)

http://www.orkambihcp.com/dosage-and-administration/drug-interaction-tool ORKAMBI® (lumacaftor/ivacaftor) Drug-drug Interaction tool - Healthcare providers can use an interactive drug-drug Interaction (DDI) finder tool to assess potential drug interactions with ORKAMBI® (lumacaftor/ivacaftor)

http://www.orkambihcp.com/patient-management-and-other-resources/treatment-considerations Starting and Maintaining ORKAMBI® (lumacaftor/ivacaftor) Therapy - Interactive view of pretreatment evaluations and ongoing monitoring recommendations for patients starting or taking ORKAMBI® (lumacaftor/ivacaftor)

http://www.orkambihcp.com/patient-management-and-other-resources/patient-beliefs-and-adherence ORKAMBI® (lumacaftor/ivacaftor) Patient Adherence - Guide to understanding how factors, including patient beliefs, may affect adherence. Open-ended questions and references to patient education resources

http://www.orkambihcp.com/patient-management-and-other-resources/orkambi-management-guide ORKAMBI® (lumacaftor/ivacaftor) Patient Management Guide - Treatment initiation and management guide for ORKAMBI® (lumacaftor/ivacaftor)

http://www.orkambihcp.com/patient-management-and-other-resources/webcast-library ORKAMBI® (lumacaftor/ivacaftor) Video library for HCPs - Healthcare provider guide to preparing patients for ORKAMBI® (lumacaftor/ivacaftor)

http://www.orkambihcp.com/patient-management-and-other-resources/mechanism-of-action-download ORKAMBI® (lumacaftor/ivacaftor) Mechanism of Action Download - Download information on the mechanism of action of ORKAMBI® (lumacaftor/ivacaftor)

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